LACRISERT (hydroxypropyl cellulose ophthalmic insert)

LACRISERT (hydroxypropyl cellulose ophthalmic insert) is a sterile, translucent, rod-shaped, water soluble, preservative-free, slow-release, prescription lubricant which is placed into the inferior cul-de-sac of the eye to treat moderate to severe dry eye syndromes.

LACRISERT acts to stabilize and thicken the precorneal tear film and prolongs the tear film breakup time which is usually accelerated in patients with dry eye states.

LACRISERT also acts to lubricate and protect the eye.

LACRISERT has been proven to relieve the following symptoms1: dryness, burning, tearing, foreign body sensation, itching, photophobia, and blurred vision. It also can be used to treat the following eye conditions: exposure keratitis, decreased corneal sensitivity and recurrent corneal erosions.

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Key Features 

  • Once a day for most people*
  • Preservative-free
  • Continuous lubrication over the course of a day*
*Individual results may vary. Some patients may require twice daily use for optimal results.

Indications and Usage

LACRISERT (hydroxypropyl cellulose ophthalmic insert) is indicated in patients with moderate to severe dry eye syndromes, including keratoconjunctivitis sicca. LACRISERT is indicated especially in patients who remain symptomatic after an adequate trial of therapy with artificial tear solutions. LACRISERT is also indicated for patients with exposure keratitis, decreased corneal sensitivity, and recurrent corneal erosions.

Important Safety Information

  • LACRISERT (hydroxypropyl cellulose ophthalmic insert) is contraindicated in patients
    who are hypersensitive to hydroxypropyl cellulose.

  • Instructions for inserting and removing LACRISERT should be carefully followed.

  • If improperly placed, LACRISERT may result in corneal abrasion. Because LACRISERT may cause transient blurred vision, patients should be instructed to exercise caution when driving or operating machinery.

  • The following adverse reactions have been reported, but were in most instances mild and temporary: transient blurring of vision, ocular discomfort or irritation, matting or stickiness of eyelashes, photophobia, hypersensitivity, eyelid edema, and hyperemia.

Please see full Prescribing Information for LACRISERT (hydroxypropyl cellulose ophthalmic insert).

LACRISERT (hydroxypropyl cellulose ophthalmic insert) : Additional information

1. LACRISERT [package insert] Madison, NJ: ATON Pharma, 2008