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* Compared to Clear Care

  1. Results from a 22-investigator, multi-site study of PeroxiClear, with a total of 440 eligible subjects. Subjects were randomized to use either PeroxiClear or Clear Care for 3 months. Subjects completed performance surveys at 2-week, 1-month, 2-month, and 3-month visits.

  2. Results from a 21-investigator, multi-site study of PeroxiClear, with a total of 297 eligible subjects who were habitual Clear Care users. After 7 days of use, subjects completed an online survey. Consumers rated the performance of PeroxiClear across a range of attributes and compared the performance to their habitual Clear Care solution.

  3. High-resolution/accurate-mass (HR/AM) mass spectrometry was used to detect and quantitate the relative amounts of surfactant retained on lenses from PeroxiClear and Clear Care solutions after 20 hours of wear. PureVision2, ACUVUE OASYS, and AIR OPTIX AQUA lenses were soaked in solutions for 12 hours prior to patients wearing lenses for 20 hours.

  4. Results of an ex vivo study measuring deposits on worn contact lenses to compare the clinical performance of PeroxiClear and Clear Care solutions. Lenses were worn daily for 1 month (silicone hydrogel and Group IV hydrogel lenses) or 3 months (gas permeable lenses). A total of 374 lenses were randomly selected for image analysis. Lenses were scored for mean density of deposits and percent coverage of deposits.

  5. Results of an in vitro study measuring deposits on ACUVUE OASYS lenses. Lenses were subjected to 14 cycles of deposition with a lipid and protein solution mimicking the human tear film followed by a cleaning regimen with either PeroxiClear or Clear Care 3% hydrogen peroxide systems. Each deposition/cleaning cycle was representative of one day of patient use. Cycled lenses (n=3) were analyzed for deposits using image analysis. After 14 cycles, lenses cleaned with PeroxiClear had only 8.0% surface coverage compared to 33.0% for lenses cleaned with Clear Care.

  6. Millward Brown Healthcare. A multi-country market research study conducted online amongst 300 soft contact lens wearers, all wearing their lenses for at least 4 days a week and using an HP solution. May/June 2011.

  7. Results of in vitro study following FDA/ISO stand-alone procedure for disinfecting products. Test solutions were modified with organic soil to create a more rigorous test condition. Primary criteria for effective disinfection are defined as a reduction in the number of bacteria by a minimum of 3 logs (99.9%) and a reduction of mold and yeast by a minimum of 1 log (90%) within the recommended disinfection time. Graphs depict mean log reduction measured after manufacturers’ recommended disinfecting time (soak only).

  8. Bausch + Lomb Patent EP0969812A1. Ophthalmic compositions including glycerine and propylene glycol. Published January 12,2000.

  9. Mean (+SD) results of residual hydrogen peroxide concentrations for 10 lens cases of PeroxiClear 3% hydrogen peroxide system. Cases were cycled one time with 10 mL aliquots of the solution dispensed and soaked in cases for the recommended regimen time of 4 hours. Residual peroxide concentrations were measured using redox titration.

  10. Epstein AB, Brujic M, Lievens CW, Sindt CW, Szczotka-Flynn LB, Townsend WD. A Clear Advantage: Learn why Clear Care Cleaning and Disinfecting Solution is the go-to peroxide system for these practitioners. Contact Lens Spectrum. Published June 2013. (Supplement, reprint CCS12020JS-D).


US/OCD/14/0037