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A female doctor explains a procedure to a patient
A female doctor explains a procedure to a patient

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Miochol™-E

(acetylcholine chloride intraocular solution)

Vitrase® (hyaluronidase Injection) Ovine, 200 USP Units/mL for
Vitrase® (hyaluronidase Injection) Ovine, 200 USP Units/mL for

VITRASE®

(hyaluronidase injection) Ovine

Miochol™-E (acetylcholine chloride intraocular solution)

IMPORTANT SAFETY INFORMATION

  • Patients with an allergy to Miochol-E or any ingredient contained in the product should not use.
  • ADVERSE REACTIONS: Infrequently, use of intraocular acetycholine has caused the cornea (the transparent layer which protects the front of the eye) to become cloudy or swollen. This may affect your vision.
    Adverse reactions that are indicative of systemic absorption have been reported rarely. These include bradycardia, hypotension, flushing, breathing difficulties, and sweating.
  • PEDIATRIC USE: Safety and effectiveness in pediatric patients have not been established.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or or call 1-800-FDA-1088.

Click here for full Prescribing Information.

Vitrase® (hyaluronidase injection) Ovine
IMPORTANT SAFETY INFORMATION

  • Patients should not use VITRASE if they have an allergy to hyaluronidase or any other ingredient in the formulation.
  • Spread of Localized Infection: Hyaluronidase should not be injected into or around infected or acutely inflamed area because of the danger of the infection spreading. Hyaluronidase should not be used to reduce the swelling of bites or stings.
  • Ocular Cornea Damage: VITRASE should not be applied directly to the cornea.
  • Adverse Reactions: The most frequently reported adverse reactions have been local injection site reactions. Hyaluronidase has been reported to enhance the adverse reactions associated with co-administered drug products. Swelling caused by fluid buildup has been reported most frequently in association with fluid infusion under the skin. Allergic and anaphylactic-like reactions have been reported, rarely.
  • Tell your doctor what other medications you are taking because some medications may be incompatible or interact with hyaluronidase.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Click here for full Prescribing Information.